By Vicente LLP, Psychedelic Alpha

Jan 8, 2025

Vicente LLP is proud to collaborate with Psychedelic Alpha—an independent newsletter and community in the field of psychedelics—on the Colorado Natural Medicine Health Act Tracker, which includes high-level statistics, anticipated recommendations, and regularly published Natural Medicine Advisory Bulletins. The bulletins will provide updates from Natural Medicine Advisory Board meetings, along with other important information related to the implementation of the NMHA and psychedelics reform in Colorado.


As of January 1st, 2025, Colorado’s Regulated Natural Medicine Program is open for business!

After nearly two years of planning and hundreds (thousands?) of hours of board, subcommittee, and stakeholder meetings, applications for facilitators are live at the the Department of Regulatory Agencies’ (DORA) Office of Natural Medicine, and for Natural Medicine Businesses at the Department of Revenue’s (DOR) Natural Medicine Division.

This is a monumental moment for the state of Colorado and the broader psychedelic movement. We want to first thank the Board, the staff of DORA and DOR, the Colorado Department of Law, and each individual stakeholder who has contributed to building a program that provides safe and equitable access to the natural medicine we all believe in.

Now that applications are open, DORA has published the following guides to assist future facilitators in navigating the licensing framework:

Additional guidance is available for Natural Medicine Businesses on Advertising and an FAQ on Local Government Approval.

However, despite the agency doing its best to provide guidance to future applicants, a few significant questions still remain unanswered, namely:

  • Will administration sessions be permitted in private residences or non-licensed health-care facilities?
  • Will the rules provide a viable option for microdosing, like Oregon?

While rules have generally been trending in a positive direction, with regulators responding to stakeholder feedback and adjusting rules accordingly, a noticeable shift in tenor has taken place during the final months of 2024 by DORA. The agency made substantial changes to rules in the eleventh hour, blatantly disregarding public feedback and input from the Natural Medicine Advisory Board (NMAB).

In this Bulletin, we examine the remaining open questions for the program, as well as several ongoing controversies, the most significant being the questions of at-home facilitation and microdosing.

An initial stakeholder meeting on rules related to at-home facilitation and microdosing is scheduled for January 6th at 1:30 p.m. MST. The final hearing will be held on January 14th at 12 p.m. MST.

If you believe access to Natural Medicine should not be limited to Healing Centers, please attend a hearing or submit written comments to [email protected]

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